产前给予发育毒物后大鼠分娩开始时间的延迟。
Delay in the onset of parturition in the rat following prenatal administration of developmental toxicants.
作者信息
White R D, Allen S D, Bradshaw W S
出版信息
Toxicol Lett. 1983 Aug;18(1-2):185-92. doi: 10.1016/0378-4274(83)90092-9.
PMID:6414113
Abstract
The duration of gestation was determined in Sprague-Dawley albino rats exposed during days 6-18 of pregnancy to diethylstilbestrol (DES) or 3,4,3',4'-tetrachlorobiphenyl (4CB). Each compound produced a delay in the onset of parturition compared to corn-oil-treated controls. The incidence of perinatal mortality was significantly elevated in animals born after 22 days of gestation in both control and treated litters.
摘要
在妊娠第6至18天暴露于己烯雌酚（DES）或3,4,3',4'-四氯联苯（4CB）的斯普拉格-道利白化大鼠中测定妊娠期。与玉米油处理的对照组相比，每种化合物都导致分娩开始延迟。在妊娠22天后出生的动物中，对照组和处理组的围产期死亡率均显著升高。
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