Hau J, Gidley-Baird A A, Teisner B, Svendsen P, Westergaard J G
Acta Endocrinol (Copenh). 1983 Sep;104(1):23-6. doi: 10.1530/acta.0.1040023.
Hypophysectomy of female mice resulted in the disappearance of pregnancy-associated murine protein-1 (PAMP-1) from the circulation within a week. Maintenance of physiological levels of oestrogen, progesterone, testosterone, LH, FSH or prolactin was not sufficient to maintain a normal PAMP-1 level in the hypophysectomized animals. However, administration of oestrogen in large doses to adult male mice with undectatable levels of circulating PAMP-1 caused PAMP-1 to appear in the blood. Testosterone treatment of females inhibited the PAMP-1 synthesis.
对雌性小鼠进行垂体切除术后，妊娠相关小鼠蛋白-1（PAMP-1）在一周内从循环系统中消失。维持雌激素、孕酮、睾酮、促黄体生成素、促卵泡生成素或催乳素的生理水平不足以使垂体切除的动物维持正常的PAMP-1水平。然而，对循环中PAMP-1水平检测不到的成年雄性小鼠大剂量施用雌激素会导致血液中出现PAMP-1。对雌性小鼠进行睾酮处理会抑制PAMP-1的合成。
