Rødahl E, Maeland J A
Acta Pathol Microbiol Immunol Scand B. 1983 Aug;91(4):285-9. doi: 10.1111/j.1699-0463.1983.tb00048.x.
The elicitation of antibodies to gonococcal lipopolysaccharide (LPS) was studied. Rabbits were immunized with whole cells of gonococci, purified LPS, or LPS linked to bovine serum albumin with glutaraldehyde. Purified LPS was not immunogenic. Anti-LPS antibodies were produced by rabbits receiving the LPS-BSA conjugate. These animals showed an earlier IgG anti-LPS antibody response than animals receiving whole bacterial cells. Antiserum to the LPS-BSA conjugate gave rise to a single precipitation line against ultrasonically disrupted gonococci, and agglutinated heat-treated cells of the bacteria.
对淋球菌脂多糖（LPS）抗体的诱导进行了研究。用淋球菌全细胞、纯化的LPS或用戊二醛与牛血清白蛋白连接的LPS对兔子进行免疫。纯化的LPS没有免疫原性。接受LPS - BSA偶联物的兔子产生了抗LPS抗体。这些动物比接受全细菌细胞的动物表现出更早的IgG抗LPS抗体反应。针对LPS - BSA偶联物的抗血清对经超声破碎的淋球菌产生单一沉淀线，并凝集该细菌的热处理细胞。
