Tonete S S, de Nóbrega F J, Sartor M E, Trindade C E, Lopez F A, Curi P R
Arch Latinoam Nutr. 1983 Mar;33(1):109-25.
Rats were submitted to protein-calorie deprivation during different periods of gestation and the body weight and mortality of offspring were evaluated at 0, 28 and 90 days of age. The body weight was considered adequate (n) when the values were up to 2 SD below the mean values of control animals, or inadequate (d) when the values were below 2 SD. Rats of the control group (C) were fed ad libitum (protein 21%), and the rats of the experimental groups were fed during all gestational period (D), during the first half (D1) or second half of pregnancy (D2), with a diet containing 1% of protein, and the intake reduced to 50%. Significant differences were observed in the ponderal evolution for all experimental groups. Group D was the most damaged, with the greatest ponderal deficiency and the greatest mortality rates. Similar behavior was observed for D2. Group D1 was similar to C with the best results and the lowest mortality rate.
在妊娠的不同时期，对大鼠进行蛋白质 - 热量剥夺，并在子代0、28和90日龄时评估其体重和死亡率。当体重值低于对照组动物平均值2个标准差时，体重被认为是不足的（d），当体重值低于平均值2个标准差以内时，体重被认为是正常的（n）。对照组（C）的大鼠自由进食（蛋白质含量21%），实验组的大鼠在整个妊娠期（D组）、妊娠前半段（D1组）或后半段（D2组），喂食含1%蛋白质的饲料，摄入量减少至50%。所有实验组在体重增长方面均观察到显著差异。D组受损最严重，体重不足最明显，死亡率最高。D2组观察到类似的情况。D1组与C组相似，结果最佳，死亡率最低。
