Knoll E, Rebel F C, Wisser H
J Clin Chem Clin Biochem. 1978 Apr;16(4):239-44.
A kinetic method is described for the determination of creatinine in serum. The method is adapted for use with Gemsaec-Fast-Analyzer. The reliability criteria of the method are reported. The only interfering substance is bilirubin, which, when present in elevated concentrations, causes an apparent decrease in the level of creatinine. This interference can be avoided by treating the sample with Fuller's earth prior to the creatinine determination. 72 sera were analysed by the kinetic method and by the Fuller's earth method without deproteinization (5). There was excellent agreement between the two methods (y=1.011 x--0.8222;r=0.9970).
本文描述了一种测定血清中肌酐的动力学方法。该方法适用于Gemsaec快速分析仪。报告了该方法的可靠性标准。唯一的干扰物质是胆红素，当胆红素浓度升高时，会导致肌酐水平明显下降。在测定肌酐之前，用富勒土处理样品可避免这种干扰。采用动力学方法和未脱蛋白的富勒土方法对72份血清进行了分析(5)。两种方法之间具有极好的一致性(y = 1.011x - 0.8222;r = 0.9970)。
