Miyazawa K, Nori D, Hilaris B S, Lewis J L
J Reprod Med. 1983 Aug;28(8):539-41.
To evaluate different methods of radiation therapy for advanced vulvar malignancy, a retrospective study was done on 33 patients treated with radiation between 1950 and 1979. Group I consisted of 18 patients treated with surgery and radiation and group II of 15 patients treated with radiation alone. The patients received several kinds of radiation therapy. Group I received radiotherapy because of local recurrence or positive lymph nodes found in the groin and/or pelvis; the overall survival in that group ranged from 3 months to 11 years. Group II received radiation only because of locally advanced disease and/or associated medical problems; the overall survival in that group ranged from 2 to 40 months. We concluded that megavoltage radiation minimized the local reaction and that better local control was obtained with a combination of photons and electrons and an interstitial implant. Postoperative radiation for positive lymph nodes prevented local recurrence but did not seem to improve survival.
为评估晚期外阴恶性肿瘤的不同放射治疗方法,对1950年至1979年间接受放射治疗的33例患者进行了一项回顾性研究。第一组由18例接受手术和放射治疗的患者组成,第二组由15例仅接受放射治疗的患者组成。患者接受了几种放射治疗。第一组因局部复发或腹股沟和/或盆腔发现阳性淋巴结而接受放射治疗;该组的总生存期为3个月至11年。第二组仅因局部晚期疾病和/或相关医疗问题而接受放射治疗;该组的总生存期为2至40个月。我们得出结论,兆伏级放射可将局部反应降至最低,并且光子和电子联合及组织间插植可实现更好的局部控制。对阳性淋巴结进行术后放射可预防局部复发,但似乎并未提高生存率。