Ohrloff C, Korte I, Doffin I, Elsing M, Hockwin O, Bartholomew R S, Clayton R, Cuthbert J, Phillips C I, Seth I
Ophthalmic Res. 1983;15(3):136-9. doi: 10.1159/000265248.
The specific activities of glutathione reductase (GR), EC 1.6.4.2, and aldolase, (ALD) EC 4.1.2.13, were determined in the homogenates of 60 cataractous lenses. Concentrations of certain plasma constituents and the morphological types of cataract of the patients were known. Investigations were aimed at establishing a possible correlation between enzyme activities and plasma constituents as well as between the specific activities of GR and ALD and type of cataract. A correlation between the specific activity of GR and the urea content of the blood could be identified. Results also indicated a relationship between the decrease in GR activity and the formation of cortical cataracts.
测定了60例白内障晶状体匀浆中谷胱甘肽还原酶（GR，EC 1.6.4.2）和醛缩酶（ALD，EC 4.1.2.13）的比活性。已知患者某些血浆成分的浓度以及白内障的形态类型。研究旨在确定酶活性与血浆成分之间以及GR和ALD的比活性与白内障类型之间可能存在的相关性。可以确定GR的比活性与血液中尿素含量之间的相关性。结果还表明GR活性降低与皮质性白内障的形成之间存在关联。
