Wei E T
Psychopharmacology (Berl). 1983;81(2):111-4. doi: 10.1007/BF00429002.
Shaking movements of the body, similar to that made by a dog when wet ('wet-dog shakes'), occur in rats in response to pharmacological stimuli and in response to stimuli associated with cold and skin irritation. In this study, shaking movements, elicited by a variety of stimuli, were inhibited by central administration of nanomolar doses of drugs that act as agonists on muscarinic, adrenergic, and opiate receptors. The brain regions that mediate the drug inhibition of shaking appear to be located in the medial preoptic area and in structures lining the aqueduct and fourth ventricle.
身体的颤抖动作，类似于狗被淋湿时的动作（“湿狗抖身”），在大鼠中会因药理学刺激以及与寒冷和皮肤刺激相关的刺激而出现。在本研究中，由多种刺激引发的颤抖动作，会被中枢给予纳摩尔剂量的、对毒蕈碱、肾上腺素能和阿片受体起激动剂作用的药物所抑制。介导药物对颤抖抑制作用的脑区似乎位于视前内侧区以及围绕中脑导水管和第四脑室的结构中。
