细菌性脑膜炎患儿抗利尿激素分泌异常综合征

The syndrome of inappropriate secretion of antidiuretic hormone in children with bacterial meningitis.

作者信息

Kaplan S L, Feigin R D

出版信息

J Pediatr. 1978 May;92(5):758-61. doi: 10.1016/s0022-3476(78)80144-9.

Abstract

Plasma concentrations of arginine vasopressin were determined by radioimmunoassay in 13 normal children, 21 patients with febrile illnesses (not bacterial meningitis), and 17 patients with bacterial meningitis. The mean +/- 1 SD concentrations of AVP in the normal children and patients with various febrile illnesses were 0.7 +/- 0.6 and 1.0 +/- 1.2 muU/ml, respectively. The mean +/- 1 SD concentration of AVP in patients with bacterial meningitis was 3.3 +/- 2.3 muU/ml. The concentrations of AVP in the patients with bacterial meningitis were significantly greater (P less than 0.001) than those noted in the normal children or children with other febrile diseases.

摘要

采用放射免疫分析法测定了13名正常儿童、21例发热性疾病（非细菌性脑膜炎）患儿和17例细菌性脑膜炎患儿的血浆精氨酸加压素浓度。正常儿童和各类发热性疾病患儿的AVP平均浓度±1标准差分别为0.7±0.6和1.0±1.2 μU/ml。细菌性脑膜炎患儿的AVP平均浓度±1标准差为3.3±2.3 μU/ml。细菌性脑膜炎患儿的AVP浓度显著高于正常儿童或患有其他发热性疾病的儿童（P<0.001）。