Book L S, Herbst J J, Stewart D
J Pediatr. 1978 May;92(5):793-7. doi: 10.1016/s0022-3476(78)80159-0.
Five infants received 10% calcium gluconate via umbilical artery catheters, which resulted in intestinal bleeding and lesions of the buttock, anus, groin, and thigh. The effects of intra-arterial calcium gluconate in two animal models were investigated. Injection of calcium into the aorta in the region of the posterior mesenteric artery resulted in immediate hyperperfusion of the descending colon; this may be an early hemodynamic response to injury in the area of colon supplied by this vessel. Injections into the arterial arcade of the rabbit ileum resulted in intestinal necrosis and villous atrophy. The use of umbilical artery catheters for administration of calcium gluconate is potentially hazardous.
五名婴儿通过脐动脉导管接受了10%的葡萄糖酸钙，这导致了肠道出血以及臀部、肛门、腹股沟和大腿的损伤。研究了葡萄糖酸钙动脉内注射在两种动物模型中的作用。在肠系膜后动脉区域向主动脉注射钙导致降结肠立即出现血流灌注过多；这可能是对该血管供应的结肠区域损伤的早期血流动力学反应。向兔回肠动脉弓注射导致肠道坏死和绒毛萎缩。使用脐动脉导管给予葡萄糖酸钙有潜在危险。
