Aurias A, Rimbaut C, Buffe D, Dubousset J, Mazabraud A
C R Seances Acad Sci III. 1983;296(23):1105-7.
The chromosomal analysis of four fresh Ewing tumours shows a translocation of the band q12 of the chromosome 22 in all the clones observed. This translocation seems to preferentially involve the band q24 of the chromosome 11. These results are in favour of a consistent translocation in Ewing's sarcoma, and are to be compared with the results obtained in other malignancies. A relation between this translocation and the location of the human oncogene c-sis on the chromosome 22 should be considered.
对四个新鲜尤因肿瘤进行的染色体分析显示，在所有观察到的克隆中均存在22号染色体q12带的易位。这种易位似乎优先涉及11号染色体的q24带。这些结果支持尤因肉瘤中存在一致的易位，并且应与在其他恶性肿瘤中获得的结果进行比较。应考虑这种易位与人类癌基因c-sis在22号染色体上的位置之间的关系。
