生长激素释放素（GRF）刺激成年男性释放具有生物活性的生长激素（GH）。
[Somatocrinin (GRF) stimulates the liberation of biologically active somatotropin (GH) in adult man].
作者信息
Sassolas G, Boissel J P, Cohen R, Chatelain P, Laporte S, Galleyrand J, Cohen H, Ferry S, Maire P
出版信息
C R Seances Acad Sci III. 1983;296(23):1113-6.
PMID:6416624
Abstract
Intravenous injection of four doses (75, 150, 300, 600 micrograms) of synthetic somatocrinin (GRF 44) greatly increases serum growth hormone concentrations in ten adult normal men in contrast to placebo. Mean peak values were identical. Plasma GH released under GRF stimulation was able to stimulate proliferation of NB2 cells.
摘要
与安慰剂相比，静脉注射四剂（75、150、300、600微克）合成生长激素释放因子（GRF 44）可显著提高十名成年正常男性的血清生长激素浓度。平均峰值相同。生长激素释放因子刺激下释放的血浆生长激素能够刺激NB2细胞增殖。
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