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小鼠对猬迭宫绦虫四槽蚴肠道免疫的研究。

Studies on intestinal immunity against tetrathyridia of Mesocestoides corti (Cestoda) in mice.

出版信息

J Parasitol. 1978 Apr;64(2):253-6.

PMID:641667
Abstract

In vitro antiparasitic effects were observed in intestinal extracts from NAMRU mice subcutaneously vaccinated with live tetrathyridia of Mesocestoides corti. All of the tetrathyridia incubated in intestinal extracts from subcutaneously vaccinated mice were dead within 8 hr and completely digested within 24 hr. Tetrathyridia incubated in intestinal extracts from mice either previously orally infected with live tetrathyridia or control mice were alive after 24 hr. A considerable number (17/20) of tetrathyridia pretreated with mouse serum from subcutaneously vaccinated mice were killed within 8 hr of incubation in intestinal extracts from untreated donor mice. The majority of the worms pretreated with either normal mouse serum or phosphate buffered saline (pH 7.2) were alive after 8 hr of incubation in intestinal extracts from untreated donor mice.

摘要

在用活的猬迭宫绦虫四膜虫皮下接种的美国海军医学研究处(NAMRU)小鼠的肠道提取物中观察到了体外抗寄生虫作用。在皮下接种小鼠的肠道提取物中孵育的所有四膜虫在8小时内死亡,并在24小时内完全消化。在先前经口感染活的四膜虫的小鼠或对照小鼠的肠道提取物中孵育的四膜虫在24小时后仍存活。用皮下接种小鼠的血清预处理的相当数量(17/20)的四膜虫在未处理的供体小鼠的肠道提取物中孵育8小时内被杀死。用正常小鼠血清或磷酸盐缓冲盐水(pH 7.2)预处理的大多数蠕虫在未处理的供体小鼠的肠道提取物中孵育8小时后仍存活。

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1
Studies on intestinal immunity against tetrathyridia of Mesocestoides corti (Cestoda) in mice.小鼠对猬迭宫绦虫四槽蚴肠道免疫的研究。
J Parasitol. 1978 Apr;64(2):253-6.
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