Sogandares-Bernal F, Voge M
J Parasitol. 1978 Aug;64(4):620-4.
7Sgamma2b antibody was detected, by fluorescein labeled antibodies, on the body surfaces and wall of excretory bladder of tetrathyridia of M. corti removed from the peritoneums of 5--24-week laboratory infections of ICR/TIMCO mice. 7Sgamma1, 7Sgamma2a, 7Sgamma3, IgM, IgA, and C3 were not found by use of the same techniques. Tetrathyridia maintained in culture medium to which pooled normal mouse, infected mouse, and horse (control) serums containing all known classes and subclasses of immunoglobulins had been added showed only mouse 7Sgamma2b on their surfaces and wall of the excretory bladder, and then only when incubated in pooled serum from infected mice. No other mouse immunoglobulin classes or subclasses were found attached to the worms, nor was any reaction obtained from tetrathyridia incubated in culture medium alone, normal mouse serum, or horse serum. This suggests a highly selective nonspecific absorption of 7Sgamma2b, or more likely demonstrates the specificity of the antibody for the parasite surfaces and wall of the excretory bladder. The possibility that 7Sgamma2b may be acting in an enhanceing mode is discussed.
利用荧光素标记抗体，在从5至24周龄经实验室感染的ICR/TIMCO小鼠腹膜中取出的柯氏中殖孔绦虫裂头蚴体表及排泄囊壁上检测到了7Sγ2b抗体。采用同样的技术未发现7Sγ1、7Sγ2a、7Sγ3、IgM、IgA和C3。在添加了含有所有已知免疫球蛋白类别和亚类的混合正常小鼠、感染小鼠及马（对照）血清的培养基中培养的裂头蚴，仅在其排泄囊的体表及壁上显示有小鼠7Sγ2b，且仅在感染小鼠的混合血清中孵育时才出现。未发现有其他小鼠免疫球蛋白类别或亚类附着于虫体，在仅含培养基、正常小鼠血清或马血清中孵育的裂头蚴也未出现任何反应。这表明7Sγ2b有高度选择性的非特异性吸附，或者更可能表明该抗体对寄生虫体表及排泄囊壁具有特异性。文中讨论了7Sγ2b可能以增强模式发挥作用的可能性。
