Di Virgilio F, Gomperts B D
FEBS Lett. 1983 Nov 14;163(2):315-8. doi: 10.1016/0014-5793(83)80843-6.
The influence of extracellular Mg2+ on Ca2+ ionophore (A23187 and ionomycin) induced secretion and changes in the cytosol pH of rabbit neutrophils suspended in Ca2+-free buffer has been investigated. While extracellular Ca2+ is obligatory for ionomycin induced secretion, we have defined conditions under which A23187 can induce secretion in Ca2+-free media. The different behaviour of these two Ca2+ ionophores is discussed on the basis of their different counter cation specificities.
研究了细胞外Mg2+对悬浮于无Ca2+缓冲液中的兔中性粒细胞中Ca2+离子载体（A23187和离子霉素）诱导的分泌以及胞浆pH变化的影响。虽然细胞外Ca2+对于离子霉素诱导的分泌是必需的，但我们已经确定了A23187在无Ca2+培养基中诱导分泌的条件。根据这两种Ca2+离子载体不同的抗衡阳离子特异性，讨论了它们不同的行为。
