Kehayov I R, Kyurkchiev S D, Davidoff M S, Galabov P G
Histochemistry. 1983;79(1):117-30. doi: 10.1007/BF00494349.
A new protein with a molecular weight of 669,000, identified in brain extracts from 4 to 69 years old subjects has been isolated and immunochemically characterized. The antigen is found in human adult brain but not in the brains of human fetuses and newborn infants or in the brains of several other species tested. Immunocytochemically, using the PAP method, the antigen is localized at the surface of some nerve cells and on astrocytes and oligodendrocytes of the cerebral cortex, corpus striatum, pons and medulla. The Golgi epithelial cells with Bergmann's fibers, and the velate and ordinary astrocytes in the cerebellum show immunoreactivity as well.
在4至69岁受试者的脑提取物中鉴定出一种分子量为669,000的新蛋白质，已对其进行分离并进行了免疫化学特性分析。该抗原存在于人类成人大脑中，但在人类胎儿和新生儿的大脑以及所测试的其他几种物种的大脑中均未发现。采用PAP法进行免疫细胞化学检测时，该抗原定位于某些神经细胞表面以及大脑皮层、纹状体、脑桥和延髓的星形胶质细胞和少突胶质细胞上。小脑中有伯格曼纤维的高尔基上皮细胞以及覆盖状和普通星形胶质细胞也显示出免疫反应性。
