Howell D N, Hartzman R J, Cresswell P
Hum Immunol. 1983 Oct;8(2):167-75. doi: 10.1016/0198-8859(83)90011-3.
The Ia-like antigens of hybrids of the B-lymphoblastoid cell line (B-LCL) WI-L2 and a subline of the T-lymphoblastoid cell line (T-LCL) HSB were examined. Antigens of the HLA-DR and MT series were analyzed by indirect immunofluorescence with chimpanzee anti-DR sera and monoclonal antibodies, and antigens of the SB series were analyzed by primed lymphocyte typing (PLT). The WI-L2 X HSB hybrids expressed antigens of each series not found on either parent cell. In each case, the novel antigens were indistinguishable from those found on SB, a B-LCL established from the same individual as HSB, and are thus presumably HSB encoded.
对B淋巴母细胞系（B-LCL）WI-L2与T淋巴母细胞系（T-LCL）HSB的一个亚系的杂交细胞的Ia样抗原进行了检测。通过用黑猩猩抗DR血清和单克隆抗体进行间接免疫荧光分析HLA-DR和MT系列的抗原，并用致敏淋巴细胞分型法（PLT）分析SB系列的抗原。WI-L2×HSB杂交细胞表达了在任一亲本细胞上均未发现的各系列抗原。在每种情况下，新抗原与在与HSB来自同一个体建立的B-LCL即SB上发现的抗原无法区分，因此推测是由HSB编码的。
