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醌衍生物对实验性肿瘤的影响。

Effects of quinone derivatives on an experimental tumor.

作者信息

de Oliveira M M, Linardi M C, Sampaio M R

出版信息

J Pharm Sci. 1978 Apr;67(4):562-3. doi: 10.1002/jps.2600670435.

Abstract

In continuation of studies on the activity of known solid tumor inhibitors, four acetylated glycosyl derivatives of 1,4-quinones were prepared and tested against Ehrlich ascitic tumor. All four compounds significantly inhibited growth of this neoplasm. UV, IR, and mass spectra are given for the three new synthetic quinone derivatives.

摘要

在对已知实体瘤抑制剂活性的研究中,制备了1,4 - 醌的四种乙酰化糖基衍生物,并针对艾氏腹水瘤进行了测试。所有四种化合物均显著抑制了这种肿瘤的生长。给出了三种新合成醌衍生物的紫外光谱、红外光谱和质谱。

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