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尼日利亚癫痫患者的后天病因(对378例患者的调查)

Acquired aetiological factors in Nigerian Epileptics (an investigation of 378 patients).

作者信息

Danesi M A

出版信息

Trop Geogr Med. 1983 Sep;35(3):293-7.

PMID:6417851
Abstract

378 classifiable epileptics attending the neurology clinics at Lagos University Teaching Hospital were investigated for acquired aetiological factors. 34.9% had identifiable aetiology. The commonest aetiological factor was childhood febrile convulsion, a factor most commonly associated with partial epilepsy with complex symptomatology. Other factors were: head injury, birth injury, CNS infections, cerebrovascular accidents, intracranial space occupying lesions and sickle cell disease; 39% of patients with partial epilepsy had acquired aetiological factors. The 61% of them without identifiable aetiology reflect inherent low seizure threshold which makes it possible for a clinically undetectable minimal organic lesion to be epileptogenic. 22.9% of patients with generalised epilepsy had identified aetiology suggesting that idiopathic epilepsy is not synonymous with generalised epilepsy and symptomatic epilepsy not exclusive to partial epilepsy.

摘要

对拉各斯大学教学医院神经科门诊的378例可分类癫痫患者进行了获得性病因调查。34.9%有可识别的病因。最常见的病因是儿童热性惊厥,这一因素最常与伴有复杂症状的部分性癫痫相关。其他因素包括:头部损伤、产伤、中枢神经系统感染、脑血管意外、颅内占位性病变和镰状细胞病;39%的部分性癫痫患者有获得性病因。其中61%无明确病因,反映出其固有的低惊厥阈值,使得临床上无法检测到的微小器质性病变也可能成为致痫因素。22.9%的全身性癫痫患者有明确病因,这表明特发性癫痫并不等同于全身性癫痫,症状性癫痫也并非部分性癫痫所特有。

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