人体内丙二酸半醛的代谢
Metabolism of malonic semialdehyde in man.
作者信息
Scholem R D, Brown G K
出版信息
Biochem J. 1983 Oct 15;216(1):81-5. doi: 10.1042/bj2160081.
Abstract
Malonic semialdehyde is formed in the alternative pathway of propionate metabolism and in the catabolism of beta-alanine. Studies of these pathways in cultured cells from a patient with mitochondrial malonyl-CoA decarboxylase deficiency indicate that malonic semialdehyde is directly converted into acetyl-CoA in man.
摘要
丙二酸半醛在丙酸盐代谢的替代途径和β-丙氨酸的分解代谢中形成。对一名线粒体丙二酰辅酶A脱羧酶缺乏症患者的培养细胞中这些途径的研究表明，在人体中丙二酸半醛可直接转化为乙酰辅酶A。
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本文引用的文献
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The catabolism of C14-labeled beta-alanine in the intact rat.完整大鼠体内C14标记的β-丙氨酸的分解代谢
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2
Aldehyde oxidation. V. Direct conversion of malonic semialdehyde to acetyl-coenzyme A.醛氧化。V. 丙二酸半醛直接转化为乙酰辅酶A。
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Propionic acid metabolism. IV. Synthesis of malonyl coenzyme A.丙酸代谢。IV. 丙二酰辅酶A的合成。
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Enzymatic conversion of beta-hydroxypropionate to malonic semialdehyde.β-羟基丙酸向丙二酸半醛的酶促转化。
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Metabolism of propionic acid in animal tissues. II. Propionyl coenzyme a carboxylation system.动物组织中丙酸的代谢。II. 丙酰辅酶A羧化系统。
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7
Metabolism of propionic acid in animal tissues. I. Enzymatic conversion of propionate to succinate.动物组织中丙酸的代谢。I. 丙酸向琥珀酸的酶促转化
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Degradation of malonic acid by rat tissues.大鼠组织对丙二酸的降解作用。
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