Briggs F H, Pelletier W T, Blanton C D
J Pharm Sci. 1978 May;67(5):735-7. doi: 10.1002/jps.2600670553.
Nine heterocyclic oxamic acid derivatives were synthesized and tested in the rat passive cutaneous anaphylactic assay as potential antiallergy agents. Some compounds also were tested for their effects on cholesterol-lipoprotein levels and for diuretic, antidiabetic, and antifertility activities in rats.
合成了九种杂环草氨酸衍生物,并在大鼠被动皮肤过敏试验中作为潜在的抗过敏剂进行了测试。还测试了一些化合物对大鼠胆固醇脂蛋白水平的影响以及利尿、抗糖尿病和抗生育活性。