来自海洋海绵的生理活性物质IV：杂环化合物。
Physiologically active substances from marine sponges IV: Heterocyclic compounds.
作者信息
Chib J S, Stempien M F, Cecil J T, Ruggieri G D, Nigrelli R F
出版信息
J Pharm Sci. 1977 Jul;66(7):1052-4. doi: 10.1002/jps.2600660743.
PMID:328855
Abstract
Several guanidine compounds were synthesized by the reaction of acid chlorides of thiophene and furan with guanidines. Some of these compounds showed antibiotic and cytotoxic activities. Series of pyrrole compounds were synthesized and found to have significant antibiotic activity.
摘要
通过噻吩和呋喃的酰氯与胍反应合成了几种胍化合物。其中一些化合物表现出抗生素和细胞毒性活性。合成了一系列吡咯化合物，发现它们具有显著的抗生素活性。
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