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Striatal dopamine metabolism in living monkeys examined by positron emission tomography.

作者信息

Garnett S, Firnau G, Nahmias C, Chirakal R

出版信息

Brain Res. 1983 Nov 28;280(1):169-71. doi: 10.1016/0006-8993(83)91187-3.

DOI:10.1016/0006-8993(83)91187-3
PMID:6418330
Abstract

Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This is the first time that the regional distribution of a neurotransmitter has been demonstrated in monkeys.

摘要

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