Marsili L, Franceschi G, Ballabio M, Oronzo G, Vigevani A, Ungheri D, Della Bruna C, Sanfilippo A
J Antibiot (Tokyo). 1983 Nov;36(11):1495-501. doi: 10.7164/antibiotics.36.1495.
A number of semisynthetic rifamycin derivatives modified at position 3 and/or 4, belonging to general structures 2 and 4 (see Scheme 1), have been obtained. The synthesis and the biological activities of the new compounds are described. Compounds 4p and 4q display very good antimycobacterial activity in mice.
