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[肺病理学中向量心电图与平均肺动脉压之间的关系]

[Relation between the vectorcardiogram and mean pulmonary arterial pressure in pulmonary pathology].

作者信息

Bury P, Calay G

出版信息

Arch Mal Coeur Vaiss. 1983 Nov;76(11):1306-15.

PMID:6419699
Abstract

Mean pulmonary artery pressure (PAP) is considered to be a valuable indicator of the severity of disease in patients with chronic lung damage. Its measurement requires minicatheterisation, an invasive technique associated with some morbidity. This study was undertaken to establish a relationship between PAP and vectorcardiography (VCG) in 76 patients with chronic lung disease. The patients were divided into three groups: Group I, PAP less than 19 mmHg; Group II, PAP between 19 and 30 mmHg; Group III, PAP greater than 30 mmHg. The patients presented with an obstructive pulmonary syndrome in 67,1% of cases, and an emphysematous syndrome in 32,9% of cases. The ECG tracing was suggestive of chronic cor pulmonale in 20 patients. The three VCG planes were analysed. The direction and amplitude of the 0,01 sec, 0,02 sec, 0,04 sec, 0,06 sec and maximum vector over each QRS loop were measured; the direction of rotation of the QRS loop and, in the horizontal plane, the duration of the terminal forces were also determined. Treatment of the angular data by Down's centre of gravity method allowed definition of the preferential direction of the vectors and of an index of precision. The statistical significance of the results was checked by the usual methods (chi-square, F test). The results confirmed the importance of the right posterior quadrant of the horizontal plane in assessing the degree of electrical overload and for evaluating the repercussions on the pulmonary circulation. In this plane, all angular positions of the 0,06 sec vector beyond -125 degrees corresponded in 9 out of 10 cases to higher than normal PAP (greater than 19 mmHg). A voltage of over 0,80 MV was always associated with higher than normal PAP. The predictive value of this method was 92%, with a specificity of 88% and a sensitivity of 39%. The VCG was also more sensitive than the ECG in assessing PAP of 19 to 30 mmHg; 25,6% of patients had deviation of the 0,06 sec vector of beyond -125 degrees in the horizontal plane whilst only 6,3% of cases had ECG criteria of chronic cor pulmonale. This study shows that simple and reliable non-invasive VCG criteria may be used to assess mean pulmonary artery pressure.

摘要

平均肺动脉压(PAP)被认为是慢性肺损伤患者疾病严重程度的一个重要指标。其测量需要使用微型导管插入术,这是一种有一定发病率的侵入性技术。本研究旨在确定76例慢性肺病患者的PAP与向量心电图(VCG)之间的关系。患者被分为三组:第一组,PAP小于19 mmHg;第二组,PAP在19至30 mmHg之间;第三组,PAP大于30 mmHg。67.1%的患者表现为阻塞性肺综合征,32.9%的患者表现为肺气肿综合征。20例患者的心电图显示有慢性肺源性心脏病。对三个VCG平面进行了分析。测量了每个QRS环在0.01秒、0.02秒、0.04秒、0.06秒时以及最大向量的方向和幅度;还确定了QRS环的旋转方向以及在水平面中终末力的持续时间。通过唐斯重心法处理角度数据,可以确定向量的优先方向和一个精度指数。结果的统计学显著性通过常用方法(卡方检验、F检验)进行检验。结果证实了水平面右后象限在评估电负荷程度和评估对肺循环的影响方面的重要性。在这个平面上,0.06秒向量超过-125度的所有角度位置,在十分之九的情况下对应于高于正常的PAP(大于19 mmHg)。超过0.80 MV的电压总是与高于正常的PAP相关。该方法的预测价值为92%,特异性为88%,敏感性为39%。在评估19至30 mmHg的PAP时,VCG也比心电图更敏感;25.6%的患者在水平面中0.06秒向量超过-125度,而只有6.3%的病例有慢性肺源性心脏病的心电图标准。这项研究表明,简单可靠的非侵入性VCG标准可用于评估平均肺动脉压。

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