鞘内注射吗啡用于儿童术后镇痛

Intrathecal morphine for postoperative pain relief in children.

作者信息

Jones S E, Beasley J M, Macfarlane D W, Davis J M, Hall-Davies G

出版信息

Br J Anaesth. 1984 Feb;56(2):137-40. doi: 10.1093/bja/56.2.137.

DOI:10.1093/bja/56.2.137

PMID:6419756

Abstract

Intrathecal morphine was given to 56 children undergoing open-heart surgery. The first 27 patients received 0.03 mg kg-1 and the other 29 received 0.02 mg kg-1. Satisfactory postoperative analgesia, lasting for 22 h or longer, was obtained in over 60% of the patients in each group. Respiratory depression occurred in six of the first group (0.03 mg kg-1), and three in the second (0.02 mg kg-1), most frequently between 3.5 and 4.5 h after the administration of the intrathecal morphine.

摘要

对56名接受心脏直视手术的儿童给予鞘内注射吗啡。前27例患者接受0.03 mg/kg，另外29例接受0.02 mg/kg。每组超过60%的患者获得了持续22小时或更长时间的满意术后镇痛效果。第一组（0.03 mg/kg）中有6例出现呼吸抑制，第二组（0.02 mg/kg）中有3例出现呼吸抑制，最常发生在鞘内注射吗啡后3.5至4.5小时之间。