Auscher C, Brouilhet H, Van der Kemp P, Rabaud M
C R Seances Acad Sci III. 1983;297(6):351-4.
Xanthine oxidase activity: NAD+-dependent form (D) and O2-dependent form (O) were carried out in cytosol supernatants of connective tissue growth (T.C.N.F.), skin tail, liver and plasma of carrageenan induced granuloma in the Rat. The specific activities of skin, liver and plasma were normal in animals with a granuloma. The total specific activity (D + O): 7.53 +/- 0.98 mU/mg protein, and the percentage of form O: 51.6 +/- 5.1 of the granulomatous tissue as compared to the tail are significantly increased. These results suggest the likely function of xanthine oxidase during the inflammatory response.
在角叉菜胶诱导的大鼠肉芽肿的结缔组织生长（T.C.N.F.）、尾皮肤、肝脏和血浆的胞质溶胶上清液中测定了依赖烟酰胺腺嘌呤二核苷酸（NAD +）的形式（D）和依赖氧（O）的形式。肉芽肿动物的皮肤、肝脏和血浆的比活性正常。肉芽肿组织的总比活性（D + O）：7.53±0.98 mU/mg蛋白质，与尾部相比，形式O的百分比：51.6±5.1，显著增加。这些结果表明黄嘌呤氧化酶在炎症反应中可能发挥作用。
