Schnapp P
Gerontology. 1984;30(1):55-9. doi: 10.1159/000212607.
In the author's experience once a day treatment of the hypertensive aged is feasible. A group of 71 cases with an average BP of 170/95 mm Hg or greater and an average age of 72 years were treated with DH ergocristine-clopamide-reserpine compound or methyldopa. The asymptomatic nature of hypertension and a realization of long-term medication accounted for the withdrawal of 18 cases (25.3%) in the first year. At the end of a 40-month period, 47 cases were still under treatment. The BP had been reduced to normal in 27 cases (57.4%) and significantly lowered in 8 cases (17%). With the exception of 1 case, all tolerated the therapy well and experienced no side effects.
根据作者的经验,对老年高血压患者进行每日一次的治疗是可行的。一组71例平均血压为170/95毫米汞柱或更高、平均年龄为72岁的患者接受了双氢麦角汀 - 氯噻嗪 - 利血平复合制剂或甲基多巴治疗。高血压的无症状性质以及对长期用药的认识导致第一年有18例(25.3%)退出治疗。在40个月疗程结束时,47例仍在接受治疗。27例(57.4%)血压已降至正常,8例(17%)显著降低。除1例患者外,所有患者对治疗耐受性良好,未出现副作用。