Goebel N, Pfluger N, Speiser K, Turina M, Rothlin M
Rofo. 1983 Dec;139(6):595-602. doi: 10.1055/s-2008-1055958.
In a prospective study (238 men, mean age 53 years) the changes of the native vessels were studied 3 months after a-c-bypass operation and 5 months after preop. angiography. Progression was defined as increase of stenoses of at least 20% or new total occlusion. Progression was significantly more frequent in vessels with than without bypass and was located proximally to the anastomoses in most cases, less frequently at the anastomoses and very rarely distally to the anastomoses. Proximal progression was significantly more frequent with patent than with occluded bypasses. Stenoses at the anastomoses were significantly more frequent with occluded than with patent bypasses. Stenoses of higher degrees had a stronger tendency for progression than slighter stenoses. Regression was rare and nearly always caused by surgery.
在一项前瞻性研究中（238名男性，平均年龄53岁），对自体血管的变化进行了研究，分别在冠状动脉搭桥手术后3个月和术前血管造影后5个月进行观察。病变进展定义为狭窄程度至少增加20%或出现新的完全闭塞。有搭桥的血管病变进展明显比无搭桥的血管更频繁，且在大多数情况下位于吻合口近端，较少发生在吻合口处，极少发生在吻合口远端。搭桥通畅时，近端病变进展明显比搭桥闭塞时更频繁。搭桥闭塞时，吻合口处狭窄明显比搭桥通畅时更频繁。高度狭窄比轻度狭窄有更强的病变进展倾向。病变消退很少见，几乎总是由手术引起。
