Setoguti T, Inoue Y, Shin M, Matsumura H
Acta Anat (Basel). 1984;118(1):54-9. doi: 10.1159/000145822.
Effects of epinephrine treatment on the rat parathyroid gland were studied morphologically. The mean number of storage granules per cell section (NSG) was rapidly decreased as early as 5 min after an injection of epinephrine and seemed to reach a minimum between 5 and 30 min. During this period, serum calcium levels (SCL) gradually rose and reached a maximum at 30 min. The ultrastructure of chief cells in these epinephrine-injected rats showed no marked difference as compared with that in control rats. In slightly hypocalcemic rats, induced previously by 2% EDTA-treatment, NSG was more rapidly decreased. It was suggested that storage granules may be released promptly by epinephrine treatments in spite of high SCL and that they are more promptly released under hypocalcemia.
从形态学角度研究了肾上腺素治疗对大鼠甲状旁腺的影响。早在注射肾上腺素后5分钟，每个细胞切片的储存颗粒平均数量（NSG）就迅速减少，并且似乎在5至30分钟之间达到最小值。在此期间，血清钙水平（SCL）逐渐升高，并在30分钟时达到最大值。与对照大鼠相比，这些注射肾上腺素的大鼠主细胞的超微结构没有明显差异。在先前通过2%乙二胺四乙酸（EDTA）处理诱导的轻度低钙血症大鼠中，NSG下降得更快。这表明，尽管血清钙水平较高，但肾上腺素治疗仍可能促使储存颗粒迅速释放，并且在低钙血症状态下释放得更迅速。
