[急性心肌梗死和原发性高血压患者血清免疫球蛋白的变化]

[Changes in serum immunoglobulins in subjects with acute myocardial infarct and essential hypertension].

作者信息

Campisi D, Paterna S, Bivona A, Cricchio I, Cilluffo P, Cannistraro F, Furitano G

出版信息

Boll Soc Ital Biol Sper. 1983 Dec 30;59(12):1796-800.

Abstract

20 (12 men and 8 women) acute myocardial infarction (AMI) patients and 17 (14 men and 3 women) patients with arterial hypertension (II degrees stage according to OMS) in comparison to controls age and sex matched, were studied, serum IgA, IgG, IgM were evaluated with radial immunodiffusion and serum IgE with RIA. Ho significant changes ef immunoglobulins were observed between hypertensive patients and controls; whereas a significant increase of IgM, IgG and IgE, with out changes of IgA, were shown in AMI patients. Serum Ig and IgM were significantly augmented in AMI patients in comparison to hypertensive patients.

摘要

研究了20例（12名男性和8名女性）急性心肌梗死（AMI）患者和17例（14名男性和3名女性）动脉高血压患者（根据世界卫生组织标准为II度），并与年龄和性别匹配的对照组进行比较。采用放射免疫扩散法评估血清IgA、IgG、IgM，采用放射免疫分析法评估血清IgE。高血压患者和对照组之间未观察到免疫球蛋白的显著变化；而AMI患者显示IgM、IgG和IgE显著增加，IgA无变化。与高血压患者相比，AMI患者的血清Ig和IgM显著升高。