Mendes C M, Carvalho S A, Amato Neto V, Novo N F, Juliano Y, Mendes E
Allergol Immunopathol (Madr). 1982 Mar-Apr;10(2):105-8.
The humoral immune response of patients with intestinal and hepato-intestinal form of Mansoni's schistosomiasis treated with a single dose of Oxamniquine was evaluated by quantitation of IgG, IgM, IgA and IgE. A constant and significant increase of IgE was observed in the majority of patients after treatment. Augmentation of serum IgE after treatment was variable, but a 3 fold increase was observed. IgG increased slightly after treatment in 6 patients, and IgM increased in 5 patients under the same conditions. However, the difference between the levels of IgG and IgM before and after treatment was not significant. IgA levels were within the normal range, before and after treatment.
通过定量检测IgG、IgM、IgA和IgE，评估了单剂量奥沙尼喹治疗的曼氏血吸虫病肠道型和肝肠型患者的体液免疫反应。治疗后，大多数患者的IgE持续且显著升高。治疗后血清IgE的升高程度各不相同，但观察到有三倍的增长。6例患者治疗后IgG略有升高，5例患者在相同情况下IgM升高。然而，治疗前后IgG和IgM水平的差异并不显著。治疗前后IgA水平均在正常范围内。
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