分离的肝细胞在叔丁基过氧化氢代谢过程中胞质钙离子浓度的升高涉及NADPH氧化和细胞内钙储存的动员。
Increase in cytosolic Ca2+ concentration during t-butyl hydroperoxide metabolism by isolated hepatocytes involves NADPH oxidation and mobilization of intracellular Ca2+ stores.
作者信息
Bellomo G, Thor H, Orrenius S
出版信息
FEBS Lett. 1984 Mar 12;168(1):38-42. doi: 10.1016/0014-5793(84)80202-1.
PMID:6423407
Abstract
Activation of phosphorylase a in hepatocytes incubated with t-butyl hydroperoxide indicates that hydroperoxide metabolism is associated with an increase in cytosolic free Ca2+ concentration which appears to be mediated by NADPH oxidation and to involve mobilization of intracellular Ca2+ stores.
摘要
在用叔丁基过氧化氢孵育的肝细胞中，磷酸化酶a的激活表明过氧化氢代谢与胞质游离Ca2+浓度的增加有关，这似乎是由NADPH氧化介导的，并且涉及细胞内Ca2+储存的动员。
Zotero 插件