Dewit L, Van Dam J, Rijnders A, van de Velde G, Ang K K, van der Schueren E
Int J Radiat Oncol Biol Phys. 1984 Feb;10(2):231-41. doi: 10.1016/0360-3016(84)90009-9.
Craniospinal irradiation is a standard treatment technique in patients who receive surgery for medulloblastoma. In most centers megavoltage photon irradiation is used, resulting in significant irradiation exposure to critical organs. In order to overcome this difficulty, we recently modified the technique applied in our center, by using high energy electrons (20 MeV) for irradiation of the spinal cord. The reliability of this technique was checked by performing dosimetry in a specially constructed wax phantom. Attention was focused upon dose variations at the junction of fields. Furthermore, the influence of vertebrae on the absorbed dose distribution of high energy electrons is presented. This technique seems to be safe and reliable in selected patients (children and teenagers).
全脑全脊髓照射是接受髓母细胞瘤手术患者的标准治疗技术。在大多数中心，使用兆伏级光子照射，这会导致关键器官受到大量辐射暴露。为了克服这一困难，我们最近对本中心应用的技术进行了改进，采用高能电子（20兆电子伏）照射脊髓。通过在特制的蜡模体中进行剂量测定来检验该技术的可靠性。重点关注野交界处的剂量变化。此外，还展示了椎体对高能电子吸收剂量分布的影响。该技术在特定患者（儿童和青少年）中似乎是安全可靠的。
