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前列腺C期癌的放射治疗与延迟雄激素剥夺治疗对比

Radiation therapy versus delayed androgen deprivation for stage C carcinoma of the prostate.

作者信息

Paulson D F, Hodge G B, Hinshaw W

出版信息

J Urol. 1984 May;131(5):901-2. doi: 10.1016/s0022-5347(17)50704-1.

DOI:10.1016/s0022-5347(17)50704-1
PMID:6423840
Abstract

Seventy-three patients with prostatic adenocarcinoma who were believed to have disease limited to the pelvis without evidence of node or bone extension were assigned randomly to either full-field pelvic radiation (40) or delayed hormonal therapy (33). The interval to first evidence of treatment failure was used as the end point of the study. Failures occurred in 13 patients who received radiation therapy and 11 who received delayed hormonal therapy. No difference in disease response could be identified between the 2 treatment groups.

摘要

73例被认为疾病局限于盆腔且无淋巴结或骨转移证据的前列腺腺癌患者被随机分为全盆腔放疗组(40例)或延迟激素治疗组(33例)。将首次出现治疗失败迹象的时间间隔作为研究终点。接受放疗的患者中有13例出现失败,接受延迟激素治疗的患者中有11例出现失败。两组治疗效果无差异。

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引用本文的文献

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J Cancer Res Clin Oncol. 1994;120 Suppl(Suppl 1):S35-8. doi: 10.1007/BF01377123.
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Postgrad Med J. 1987 Dec;63(746):1055-60. doi: 10.1136/pgmj.63.746.1055.
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Periodic health examination, 1991 update: 3. Secondary prevention of prostate cancer. Canadian Task Force on the Periodic Health Examination.定期健康检查,1991年更新版:3. 前列腺癌的二级预防。加拿大定期健康检查特别工作组。
CMAJ. 1991 Sep 1;145(5):413-28.