Liberti M, Tenaglia R, De Berardinis E, Gentile V
Minerva Med. 1984 Feb 28;75(8):391-4.
However adequately treated, surface carcinomas of the bladder recur sooner or later with infiltration found in about 10% of cases. Any development that may offer therapeutic progress and reduce the incidence of recurrences is therefore of primary importance. Two homogeneous groups of patients were selected for the present study: 35 were given Adriamycin and 25 Mitomycin C. In evaluating results, the incidence of recurrences in relation to the primary neoplasia and the existence of single or multiple tumors was analysed. It is concluded that Mitomycin C in association with either T.U.R. or T.V.R. is a particularly useful and indubitably effective form of topical chemotherapy in cases of single or multiple primary neoplasias.
无论治疗多么充分，膀胱表浅癌迟早会复发，约10%的病例会出现浸润。因此，任何可能带来治疗进展并降低复发率的进展都至关重要。本研究选取了两组同质患者：35例给予阿霉素，25例给予丝裂霉素C。在评估结果时，分析了与原发性肿瘤相关的复发率以及单发或多发肿瘤的存在情况。得出的结论是，丝裂霉素C联合经尿道切除术（T.U.R.）或经尿道汽化术（T.V.R.）是治疗单发或多发原发性肿瘤时一种特别有用且无疑有效的局部化疗方式。
