The physical effects of visco elastic substances on human donor cornea.

A case of corneal graft operation using chondroitin sulphate (CDS-TM) to protect the endothelium, highlights the surgical difficulties encountered as a result of the severe dehydration effects on the donor corneal button produced by the CDS. In vitro experiments comparing Healonid and CDS on 8 mm excised donor corneal buttons from three pairs of human eyes, confirms this effect with CDS which was absent with Healonid.