Houpt K A, Shepherd P, Hintz H F
Lab Anim Sci. 1978 Apr;28(2):173-7.
Two methods for producing peripheral anosmia in the dog were described. One method involved infusion of 3.5% zinc sulfate into the nasal cavity. An anosmia lasting at least 6 weeks, and, in most cases, for several months, was produced. A second technique, producing short periods of reversible anosmia, was the insertion of a tracheostomy tube with inflatable cuff. Inflation of the cuff prevented the dogs from inhaling air over the olfactory mucosa. Deflation of the cuff restored functional olfaction. The advantages and disadvantages of each technique were discussed.
描述了两种在犬类中产生外周嗅觉丧失的方法。一种方法是将3.5%的硫酸锌注入鼻腔。可产生至少持续6周、且在大多数情况下持续数月的嗅觉丧失。第二种技术可产生短期可逆性嗅觉丧失，即插入带有可充气袖带的气管造口管。袖带充气可防止犬类通过嗅觉黏膜吸入空气。袖带放气可恢复嗅觉功能。讨论了每种技术的优缺点。
