Micic S
Acta Eur Fertil. 1983 Sep-Oct;14(5):337-40.
In a group of 270 infertile men serum FSH, LH and prolactin levels were estimated and testicular biopsy was done on all subjects. This investigation showed highly significant influence of histologic appearance on serum FSH and LH but not on serum prolactin levels. Significant elevation of serum FSH level was first detected in men with spermatogenic arrest at the level of the primary spermatocyte, but the greatest number was in men without any germ cell in the seminiferous tubules. Serum LH level depended very much on the presence or absence of germ cells in the seminiferous tubules and were significantly elevated only in cases with seminiferous tubules deprived of the germ cells. According to this study serum FSH and LH levels were found to be good discriminator of testicular histologies.
对270名不育男性进行了血清促卵泡激素（FSH）、促黄体生成素（LH）和催乳素水平测定，并对所有受试者进行了睾丸活检。该研究表明，组织学表现对血清FSH和LH有高度显著影响，但对血清催乳素水平无影响。血清FSH水平显著升高首先在初级精母细胞水平发生生精停滞的男性中检测到，但数量最多的是曲细精管中没有任何生殖细胞的男性。血清LH水平很大程度上取决于曲细精管中生殖细胞的有无，仅在曲细精管缺乏生殖细胞的情况下显著升高。根据这项研究，发现血清FSH和LH水平是睾丸组织学的良好鉴别指标。
