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[精子发生障碍患者血清中的催乳素水平]

[Prolaction level in the serum of patients with disorders of spermatogenesis].

作者信息

Krause W

出版信息

Hautarzt. 1978 Feb;29(2):77-81.

PMID:632089
Abstract

In 183 out patients of our department FSH, LH, prolactin and testosterone were measured in one single serum sample. In 43 of these, measurements were done prior and 30 min after injection of LH-RH and TRH. An analysis of the ejaculate was performed in each case. If prolactin levels are grouped according to sperm count or testosterone levels, means of prolactin do not differ significantly between these groups. Some individual levels exceed the normal range. The TRN stimulated prolactin levels are lowered when related to high testosterone levels. Significantly statistical correlations do not exist. Mean FSH levels show a clear depression related to high sperm counts and high testosterone levels. A significantly statistical correlation is found between FSH, LH and prolactin levels each. Determination of prolactin in patients with fertility disturbances may be helpful to detect a hyperprolactinemia, which possibly causes inhibition of the spermatognesis.

摘要

在我科的183例门诊患者中,采集单一血清样本检测促卵泡生成素(FSH)、促黄体生成素(LH)、催乳素和睾酮。其中43例在注射促黄体生成素释放激素(LH-RH)和促甲状腺激素释放激素(TRH)前及注射后30分钟进行了检测。对每例患者的精液进行了分析。如果根据精子计数或睾酮水平对催乳素水平进行分组,这些组之间催乳素的平均值没有显著差异。一些个体水平超过正常范围。与高睾酮水平相关时,促甲状腺激素释放激素(TRN)刺激的催乳素水平会降低。不存在显著的统计学相关性。平均FSH水平与高精子计数和高睾酮水平相关时呈现明显下降。FSH、LH和催乳素水平之间均发现显著的统计学相关性。对生育障碍患者进行催乳素测定可能有助于检测高催乳素血症,其可能导致精子发生抑制。

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