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乙琥胺用药期间发生再生障碍性贫血。采用大剂量甲基强的松龙治疗。

Aplastic anemia during ethosuximide medication. Treatment with bolus-methylprednisolone.

作者信息

Seip M

出版信息

Acta Paediatr Scand. 1983 Nov;72(6):927-9. doi: 10.1111/j.1651-2227.1983.tb09845.x.

DOI:10.1111/j.1651-2227.1983.tb09845.x
PMID:6424403
Abstract

A girl, born in 1975, developed severe aplastic anemia in November 1982 while on ethosuximide monotherapy for petit mal epilepsy, about 3 months after starting the ethosuximide medication. She was treated with bolus-methylprednisolone as described by Bacigalupo et al. (13), transfusions and antibiotics. During the third week on this regimen slight improvements in granulocyte and reticulocyte counts were demonstrated, and after approximately 6 weeks she was in stable condition without further need of transfusions. Blood status should be checked regularly during ethosuximide therapy, particularly during the first 6 months.

摘要

一名出生于1975年的女孩,在1982年11月开始使用乙琥胺单药治疗小儿癫痫约3个月后,出现了严重再生障碍性贫血。她接受了Bacigalupo等人(13)描述的大剂量甲基强的松龙治疗、输血和抗生素治疗。在该治疗方案的第三周,粒细胞和网织红细胞计数略有改善,大约6周后她病情稳定,无需进一步输血。在乙琥胺治疗期间,尤其是前6个月,应定期检查血液状况。

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Aplastic anemia during ethosuximide medication. Treatment with bolus-methylprednisolone.乙琥胺用药期间发生再生障碍性贫血。采用大剂量甲基强的松龙治疗。
Acta Paediatr Scand. 1983 Nov;72(6):927-9. doi: 10.1111/j.1651-2227.1983.tb09845.x.
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