Pinilla R F, Cano A, Boto L, Pestaña A
Biochem Biophys Res Commun. 1984 Mar 30;119(3):1141-6. doi: 10.1016/0006-291x(84)90894-5.
A transitory increase in ornithine decarboxylase activity has been observed soon after food removal from Dictyostelium discoideum amoeba. This increase can be prevented by supplementation of the differentiation buffer with the 11 amino acids known for their ability to retard the development of this slime mold. Lysine can replace the amino acid mixture with an apparent inhibition constant of 50 micromolar. This inhibition by lysine, which was only observed in vivo, took place within 5 min and was readily reversed upon lysine removal.
在盘基网柄菌变形虫去除食物后不久，观察到鸟氨酸脱羧酶活性出现短暂增加。通过在分化缓冲液中补充11种已知能够延缓这种黏菌发育的氨基酸，可以防止这种增加。赖氨酸可以替代氨基酸混合物，其表观抑制常数为50微摩尔。赖氨酸的这种抑制作用仅在体内观察到，在5分钟内发生，并且在去除赖氨酸后很容易逆转。
