Desmadryl G, Raymond J, Sans A
C R Acad Sci III. 1984;298(8):223-8.
Unitary recordings of spontaneous activity were performed from vestibular ganglion perikaria and axons of Mouse inner ear explants. The latter were from 1-11 day postnatal mice and were maintained in vitro at 37 degrees C, in a defined bathing medium. Spontaneous action potentials were obtained at each developmental stage and presented the distinctive features of the in vivo recorded activities during normal development. On the 3rd day post partum the recorded activities were of the immature type, with slow irregular discharge frequencies. In ganglia 3 to 9 days post partum the spike frequencies increased and the discharges exhibited 3 distinct firing patterns. This electrophysiological maturation of vestibular receptors is discussed in comparison with the morphological maturation of the vestibular organ during the same postnatal period.
对小鼠内耳外植体的前庭神经节周缘核和轴突进行了自发活动的单一记录。后者取自出生后1至11天的小鼠，并在37摄氏度的特定浴液中于体外培养。在每个发育阶段都记录到了自发动作电位，这些电位呈现出正常发育过程中体内记录活动的独特特征。产后第3天记录到的活动属于未成熟类型，放电频率缓慢且不规则。在产后3至9天的神经节中，峰值频率增加，放电表现出3种不同的发放模式。本文将前庭感受器的这种电生理成熟与同一出生后时期前庭器官的形态成熟进行了比较讨论。
