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[男性不育症的临床研究]

[Clinical study of male infertility].

作者信息

Nakamoto T, Nagafuji T, Seo K, Nakahara M, Kume T, Yasukawa A

出版信息

Hinyokika Kiyo. 1983 Aug;29(8):885-91.

PMID:6426271
Abstract

A statistical analysis was performed on infertile male patients who visited our urological clinic between Jan. 1976 and Dec. 1981. The incidence of infertile male was 9.9% of the total male out-patients. Age distribution of most of the patients ranged from 25 to 34 years old. Infertile period was most commonly within 5 years after they had married. In semen analysis, the cases of azoospermia and oligozoospermia (less than 50 x 10(6)/ml) accounted for 80% of all the infertile males. Testicular histology showed hypospermatogenesis or "Sertoli cell only" in most patients (more than 84.2%) who received testicular biopsy. Decrease in testicular volume was accompanied by an increase in the serum levels of luteinizing hormone and follicle stimulating hormone, but there was no relationship between testicular volume and testosterone. Most of the patients with a testicular volume of less than 12 ml were azoospermic. This suggests that there may be a suppression of spermatogenesis in small testes.

摘要

对1976年1月至1981年12月期间到我们泌尿外科门诊就诊的男性不育患者进行了统计分析。男性不育患者的发病率占男性门诊患者总数的9.9%。大多数患者的年龄分布在25至34岁之间。不育期最常见于婚后5年内。在精液分析中,无精子症和少精子症(少于50×10⁶/ml)病例占所有不育男性的80%。睾丸组织学显示,在接受睾丸活检的大多数患者(超过84.2%)中存在精子发生减少或“仅支持细胞”现象。睾丸体积减小伴随着黄体生成素和卵泡刺激素血清水平的升高,但睾丸体积与睾酮之间没有关系。大多数睾丸体积小于12ml的患者无精子症。这表明小睾丸可能存在精子发生抑制。

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