对控制山羊红细胞多态性变异的五个基因位点的研究。

An investigation of five genetic loci controlling polymorphic variants in the red cells of goats.

作者信息

Tucker E M, Clarke S W, Osterhoff D R, Groenewald J

出版信息

Anim Blood Groups Biochem Genet. 1983;14(4):269-77. doi: 10.1111/j.1365-2052.1983.tb01084.x.

DOI:10.1111/j.1365-2052.1983.tb01084.x

Abstract

Results of a joint study carried out in South Africa and England to search for new genetic markers in the blood of goats are presented. Haemoglobin (Hb) phenotypes were reinvestigated with the technique of isoelectric focusing; frequencies in different goat breeds are given. Anaemic Hb type A, AB and B goats all produced a Hb C with an identical electrophoretic pattern. All goats tested had identical carbonic anhydrase (CA) types, but showed polymorphism of 'X' protein. Preliminary results indicated that nucleoside phosphorylase (NP) may be polymorphic.

摘要

本文展示了在南非和英国联合开展的一项研究成果，该研究旨在寻找山羊血液中的新基因标记。采用等电聚焦技术对血红蛋白（Hb）表型进行了重新研究，并给出了不同山羊品种中的频率。贫血型Hb A、AB和B型山羊均产生了具有相同电泳图谱的Hb C。所有测试山羊的碳酸酐酶（CA）类型均相同，但显示出“X”蛋白的多态性。初步结果表明，核苷磷酸化酶（NP）可能具有多态性。