头孢匹胺的体外抗菌活性。
In vitro antibacterial activity of cefpiramide.
作者信息
Pfaller M A, Niles A C, Murray P R
出版信息
Antimicrob Agents Chemother. 1984 Mar;25(3):368-72. doi: 10.1128/AAC.25.3.368.
Abstract
A microbroth dilution method was used to measure the MICs of cefpiramide (SM 1652), cefotaxime, moxalactam, ceftazidime, cefoperazone, ceftriaxone, piperacillin, and mezlocillin against 921 isolates of gram-negative (701) and gram-positive (220) bacteria. The activity of cefpiramide was equivalent to those of piperacillin and mezlocillin against members of the family Enterobacteriaceae and gram-positive isolates, including enterococci. Cefpiramide had equivalent or slightly greater activity against Pseudomonas aeruginosa than the other beta-lactam antibiotics tested.
摘要
采用微量肉汤稀释法测定头孢匹胺（SM 1652）、头孢噻肟、拉氧头孢、头孢他啶、头孢哌酮、头孢曲松、哌拉西林和美洛西林对921株革兰氏阴性菌（701株）和革兰氏阳性菌（220株）的最低抑菌浓度（MIC）。头孢匹胺对肠杆菌科细菌和革兰氏阳性菌（包括肠球菌）的活性与哌拉西林和美洛西林相当。头孢匹胺对铜绿假单胞菌的活性与其他受试β-内酰胺类抗生素相当或略强。
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