Abou-Madi M, Trop D, Morin L, Olivier A
Can Anaesth Soc J. 1984 May;31(3 Pt 1):255-62. doi: 10.1007/BF03007885.
This study determined the cardiovascular effects of percutaneous radiofrequency coagulation of the Gasserian ganglion, performed under neuroleptanalgesia and intermittent ultrashort-acting barbiturate anaesthesia. Twelve ASA physical status class II patients were studied. Highly significant increases in mean heart rate and arterial blood pressure followed the insertion of the cannula electrode into the Gasserian ganglion (p less than 0.001). In six randomly assigned patients severe tachycardia and hypertension also accompanied the progress of the thermal lesion (p less than 0.0001). Three patients developed premature ventricular contractions, and two developed significant ST segment depression. Intravenous nitroglycerin, used during current generation, successfully controlled the hypertensive response in the other six patients. In percutaneous thermocoagulation of the Gasserian ganglion the patient's co-operation is essential. In addition to providing suitable operating conditions for both surgeons and patient, we should also be able to maintain normal and stable cardiovascular haemodynamics. Intravenous nitroglycerin used as an adjunct to light general anaesthesia safely maintained intraoperative normotension. It is also suggested that patients with coronary artery disease be adequately monitored and protected during the procedure.
本研究确定了在神经安定镇痛和间歇性超短效巴比妥类麻醉下进行的经皮半月神经节射频凝固术的心血管效应。研究了12例美国麻醉医师协会(ASA)身体状况分级为II级的患者。将套管电极插入半月神经节之后,平均心率和动脉血压显著升高(p<0.001)。在6例随机分组的患者中,严重心动过速和高血压也伴随热损伤的进展出现(p<0.0001)。3例患者出现室性早搏,2例出现明显的ST段压低。在通电期间使用静脉注射硝酸甘油成功控制了另外6例患者的高血压反应。在经皮半月神经节热凝术中,患者的配合至关重要。除了为外科医生和患者提供合适的手术条件外,我们还应能够维持正常和稳定的心血管血流动力学。静脉注射硝酸甘油作为浅全身麻醉的辅助药物可安全维持术中血压正常。还建议在手术过程中对冠心病患者进行充分监测和保护。