狒狒急性蛛网膜下腔出血的实验研究：脑血容量、血流、电活动及含水量的变化
An experimental study of acute subarachnoid haemorrhage in baboons: changes in cerebral blood volume, blood flow, electrical activity and water content.
作者信息
Kuyama H, Ladds A, Branston N M, Nitta M, Symon L
出版信息
J Neurol Neurosurg Psychiatry. 1984 Apr;47(4):354-64. doi: 10.1136/jnnp.47.4.354.
Abstract
Subarachnoid haemorrhage following transection of the posterior artery was produced in 10 baboons. Cerebral blood volume (CBV) decreased transiently after subarachnoid haemorrhage. Two basic patterns of intracranial pressure (ICP) were observed; in one ICP returned to normal but in the other it remained elevated. In this latter group four out of five animals showed an increase in CBV above the original level. There were delays in sensory conduction (measured using somatosensory evoked potentials) bilaterally; those on the contralateral side to the bleed were correlated with ICP whereas other factors are implicated on the ipsilateral side. Initial flow reduction and restoration of cerebral blood flow were both correlated with water content.
摘要
在10只狒狒身上造成了后动脉横断后的蛛网膜下腔出血。蛛网膜下腔出血后脑血容量（CBV）短暂下降。观察到两种基本的颅内压（ICP）模式；一种模式下ICP恢复正常，但另一种模式下ICP持续升高。在后一组中，五分之四的动物CBV高于原始水平。双侧感觉传导（使用体感诱发电位测量）出现延迟；出血对侧的延迟与ICP相关，而同侧的延迟则与其他因素有关。最初的血流减少和脑血流恢复均与含水量相关。
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