Barański B, Krysiak B, Popińska E
Med Pr. 1978;29(1):21-4.
The studies carried out aim at comparing and determining the usefulness of two methods most frequently used to evaluate the sensitizing properties of chemical compounds. In the studies, compounds of known sensitizing properties have been used: potassium dichromate and 2,4-dinitrochlorobenzene. Comparison of the percentage of sensitized guinea--pigs, intensity of sensitizing reaction and the time at which the reaction is being kept up, indicates a greater usefulness of Magnusson and Kligman's method for routine evaluation of sensitizing properties of chemical compounds.
所开展的研究旨在比较并确定两种最常用于评估化合物致敏特性的方法的有效性。在这些研究中，使用了已知致敏特性的化合物：重铬酸钾和2,4-二硝基氯苯。对致敏豚鼠的百分比、致敏反应强度以及反应持续时间的比较表明，Magnusson和Kligman方法在常规评估化合物致敏特性方面更具有效性。
