Rinne A, Räsänen O, Järvinen M, Dammert K, Kallioinen M, Hopsu-Havu V K
Acta Histochem. 1984;74(1):75-9. doi: 10.1016/S0065-1281(84)80030-6.
Acid cysteine proteinase inhibitor ( ACPI ) and neutral cysteine proteinase inhibitor ( NCPI ) were localized in human epidermal malignancies by the unlabelled peroxidase-antiperoxidase complex method. Basaliomas did not contain ACPI or NCPI . In spinous, metatypic , and clear cell carcinomas of the epidermis, both inhibitors were located in the cytoplasm and sometimes on the cell membranes of the differentiated carcinoma cells. The inhibitors were not seen in the 1 or 2 most "basal" cells layers of the carcinoma islets. The locations of both inhibitors were similar, and the staining for ACPI was usually more intense than staining that NCPI .
采用非标记过氧化物酶-抗过氧化物酶复合物法，对酸性半胱氨酸蛋白酶抑制剂（ACPI）和中性半胱氨酸蛋白酶抑制剂（NCPI）在人类表皮恶性肿瘤中的定位进行了研究。基底细胞瘤不含ACPI或NCPI。在表皮的棘状、化生型和透明细胞癌中，两种抑制剂均位于分化癌细胞的细胞质中，有时也位于细胞膜上。在癌巢最“基底”的1或2层细胞中未见抑制剂。两种抑制剂的定位相似，ACPI的染色通常比NCPI的染色更强烈。
